Low Dose Immunotherapy (LDI) – Chronic Lyme Disease

Very common, complicated, frequent. Finally being accepted by mainstream medicine. Likely a loss of immune tolerance.

Many symptoms including:

  1. Chronic Encephalomyelitis – including headaches, migraine headaches, cognitive impairment, brain fog, vertigo, imbalance, leg weakness, awkward gait, facial palsy, tremors, visual-spatial dysfunction, memory loss (short and or long term).
  2. Join pain and swelling – often shooting pain/tingling extremities. Knees, elbows, wrists, hips, shoulders Lyme Arthritis.
  3. Fatigue – often severe
  4. Palpitations
  5. Bladder symptoms
  6. Lab tests often negative


  • Multiple bacteria including Burgdorferi, Borrelia, Bartonella, and Babesia – at least 50 bacteria have been implicated in Chronic Lyme Disease.
  • Multiple viruses – including Herpes Simplex, Epstein Barr, Cytomegalic Virus.
  • Multiple antibiotics – IV antibiotics in severe cases.

I am concerned with the low success rate with current therapies. Too many people are suffering.

Low Dose Immunotherapy – LDI

Lyme Disease is an inflammatory, autoimmune disorder. The immune system no longer tolerates the internal body environment. Current therapies, including multiple antibiotics simultaneously are often ineffective.

An autologous specimen1 (from one's own body) is dissolved in distilled water/sterilized and stored in a refrigerator. For Dr. Vincent, the same sample has been effective for six years.

Autologous specimens contain the microorganisms affecting the individual patient suffering from Chronic Lyme.

The mechanism of action is the same as Low Dose Allergen (LDA) – increase T regulator cells to impact CD4 (helper), CD8 (killer), and B cells. Beta Glucaronidase – natural biological response modifier – up regulator of lymphatic immune system.

Dr. Ty Vincent in 2011, a brilliant physician, recommended autologous sample from patients. For Lyme Disease, stool sample is best source. One's own sample is diluted to a homeopathic dilution that with the right dilution frequently treatment is very effective for Chronic Lyme Disease.

Dilutions are prepared from 1C up to 30C. Over the past five years, Dr. Vincent and Dr. Butch Shrader have started from 6C initially to currently 15C. Starting dose depends on each patient's history. For severe Lyme, starting at 22-30C will be considered with the goal being to start at a weaker strength and go to stronger in order to avoid flares.


  1. If 15C provides excellent response rapidly this is the core dose.
  2. If 15C causes a flare of symptoms, 16C is given seven weeks later. If the flare is severe, subsequential dilutions can be adjusted, for ex: 16C —> 19C with excellent response – this is the treatment dose.
  3. If 15C is ineffective, every 10-14 days stronger dilutions 15C-14C-13C, etc. is used until treatment dose work.
  4. Fractionation – ex: 15.5C (between 15-16) occasionally is the correct treatment dose.

LDI Summary:

  1. good response —> same
  2. worse —> weaker
  3. no response —> stronger

LDI can be given intradermal or sublingual. I prefer sublingual as it can be done at home with fewer patient visits avoiding painful intradermal injections. However, intradermal treatment will be considered for each patient.

Treatment: .01 ml. Beta Glucaronidase used same as Low Dose Allergen (LDA) with .04 ml. of optimal homeopathic dilution. Treatment is every 7-8 weeks – if doing well, longer time between treatment doses.

Diet: avoid known allergic foods for 2 weeks. Limit exposure to cats, dogs, dust, and molds if these are allergic triggers.

Flares may require anti-inflammatory medications – Prednisone.

GOAL: find the CORE DOSE to promote tolerance!

Once the CORE DOSE for the autologous LDI is found, other LDI treatments will be considered.

Dr. Ty Vincent treats Chronic Lyme Disease with Lyme Mix containing a number of bacteria and separate vials of Babesia, Bartonella, Borrelia, and Ehrlichia/Coxiella.

The protocol I follow for the autologous stool is the same.

Cost: Please call the office for fees and scheduling

To follow patients efficiently and promptly, weekly email finding the dose – one paragraph summary of the week to include naming the five worst problems that week and a grading scale of 1-10 good and 1-10 flare.

1The autologous sample will be compounded by Professional Arts Pharmacy in Baltimore, Maryland. I have an excellent, long-term, relationship with this pharmacy and prefer that the complex preparation of the autologous sample be prepared by an expert.